Welcome to our site ...

Links to our lab & research are up on top.

Our three Most Recent Publications - and interesting "behind the scenes" stories

1) Guardino, K.M., Sheftic, S.R., Slattery, R.E., & Alexandrescu, A. (2009) “Relative stabilities of conserved and non-conserved structures in the OB-fold superfamily”. Int. J. Mol. Sci. 10, 2412-2430.

Like all of our best papers, this one was very hard to publish. Judge for yourselves, we're proud of it!

.2) Patil, S.M., Xu, S., Sheftic, S. & Alexandrescu, A. (2009) “Dynamic alpha-helix structure of micelle-bound human amylin”. J. Biol. Chem. 284, 11982-11991.

This whole structure was done with 1 mg of sample and a total cost of ~ $3,000. Of that, $800 was journal page charges. Take that Structural Genomics Initiatives!!!

3) Alexandrescu, A. T. & Croke, R.L. (2008) “NMR of Amyloidogenic proteins”, in Protein Misfolding (O’Doherty C.B., and Byrne, A.C eds.) Nova Publishers, Hauppauge, NY. ISBN 978-1-60456-881-3

Andrei was on sabbatical and decided to write a book chapter. As with most of our reviews, the review is written first (can be used as fodder for grant intros) and *then* we start working in that field. We've been told it's a good review!